Fluoroquinolones: Boxed Warning to be added for risk of tendon rupture and tendinitis
The U.S. Food and Drug Administration, the american counterpart to the Saudi Food and Drug Authority (SFDA), notified healthcare professionals that a BOXED WARNING and Medication Guide are to be added to the prescribing information to strengthen existing warnings about the increased risk of developing tendinitis and tendon rupture in patients taking fluoroquinolones for systemic use.....more

Everolimus in patients with rheumatoid arthritis receiving concomitant methotrexate
Everolimus, a proliferation signal inhibitor with disease-modifying properties, may be useful in treating rheumatoid arthritis (RA). This proof-of-concept study assessed efficacy and safety of everolimus in combination with methotrexate (MTX) in patients with refractory RA.....more

Combination Endoscopic and Drug Therapy to Prevent Variceal Rebleeding in Cirrhosis
Combining endoscopic therapy and β-blockers may improve outcomes in patients with cirrhosis and bleeding esophageal varices.....more

Metformin versus Insulin for the Treatment of Gestational Diabetes

The effect of orlistat and ezetimibe, alone or in combination, on serum LDL and small dense LDL cholesterol levels in overweight and obese patients with hypercholesterolaemia