Vitamins B12, B6, and Folic Acid for Onset of Depressive Symptoms in Older Men: Results From a 2-Year Placebo-Controlled Randomized Trial 26 Sha'ban 1429 (H) Equal 27 August 2008 (G)Objective: To examine whether use of vitamins B12, B6, and folate was associated with reduced severity of depressive symptoms and 2-year incidence of clinically significant depression. ..more
Behavioral Therapy to Enable Women with Urge Incontinence to Discontinue Drug Treatment 11 Sha'ban 1429 (H) Equal 12 August 2008 (G) Women with urge urinary incontinence are commonly treated with antimuscarinic medications, but many discontinue therapy.....more
Outcomes of Nevirapine and Efavirenz-Based Antiretroviral Therapy When Coadministered With Rifampicin-Based Antitubercular Therapy 11 Sha'ban 1429 (H) Equal 12 August 2008 (G)Objective, To assess the effectiveness and tolerability of concomitant efavirenz- or nevirapine-based combination antiretroviral therapy and rifampicin-based antitubercular therapy.....more
Efficacy and tolerability of combination therapy with valsartan/ hydrochlorothiazide in the initial treatment of severe hypertension 09 Sha'ban 1429 (H) Equal 10 August 2008 (G)Most patients with severe hypertension are at high risk for cardiovascular events and require prompt blood pressure (BP)-lowering and combination therapy to achieve BP goals. This study evaluated the therapeutic efficacy and tolerability of initial treatment with the combination of valsartan and hydrochlorothiazide (HCTZ) compared with valsartan monotherapy in patients with severe hypertension.....more
The cardiovascular safety of rosiglitazone 09 Sha'ban 1429 (H) Equal 10 August 2008 (G)Thiazolidinediones (rosiglitazone, pioglitazone) influence insulin sensitivity and are used for the treatment of Type 2 diabetes. Rosiglitazone achieves sustained improvements in glycaemic control, whilst having pleiotropic effects on cardiovascular risk factors. However, analysis of cardiovascular outcomes has been controversial.....more