Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
Potential Benefits of Black Seed Oil Supplementation on Asthma Inflammation and Outcomes	King Abdulaziz University Hospital	Completed	Black Cumin Oil	2	95-15	KAUH-J
"Postoperative Analgesic Effect of Dexmedetomidine as an Adjunct to Ropivacaine Administration in Wound Infiltration for Modified Radical Mastectomy- A Randomized controlled Trial"	King Abdullah Medical City, Makkah	Ongoing	DEXMEDETOMIDINE	2	14-119	KAMC
Phase IIIb, Randomized Multicentre Comparative Trial to Evaluate the Long Term Effectiveness & Safety of the use of Carbaglu® in Patients with Propionic Acidemia (PA) or Methylmalonic Acidemia (MMA)	KAIMRC	Ongoing	Carglumic acid	3	IIT-OE-2013-001	NGHA-R
Phase III, Single-arm, Open-label, International, Multi-centre Study to Evaluate the Efficacy and Safety of Lomitapide in Paediatric Patients with Homozygous Familial Hypercholesterolaemia (HoFH) on Stable Lipid-lowering Therapy	Amryt Pharmaceuticals DAC	Ongoing	LOMITAPIDE	3	APH-19	King Abdulaziz Medical City NG (Riyadh)
Phase IIb Primary Vaccination Study to Evaluate Non-Inferiority & Persistence of the Immune Response of GSK Biologicals' MenACWY Conjugate Vaccine (Intramuscularly) vs Mencevax ACWY (Subcutaneously) to Healthy Subjects (11-55 Years of Age)	Gsk	Completed	Meningococcal ACWY Conjugate Vaccine	3b	107402	NGHA-R
Phase II/III randomized multicentre study comparing neoadjuvant chemoradiotherapy followed by consolidation chemotherapy to neoadjuvant chemoradiotherapy alone in non-metastatic rectal cancer patients.	King Abdullah Medical City, Makkah	Ongoing	Capecitabine / oxaliplatin / FOLINIC Acid / FLUOROURACIL	2	IRB#17-329 version2	KAMC
Phase II study of the efficacy of metronomic capecitabine chemotherapy as a maintenance treatment in advanced triple negative breast cancer	King Abdullah Medical City	Ongoing	Capecitabine	2	20-611	King Abdullah Medical City (Makkah)
Phase I/II Study of a Lentigen® CD19 Chimeric Antigen Receptor (CAR) T Cells in Adult patients with relapsed/refractory CD19 Positive Non-Hodgkin’s Lymphoma (NHL) using a Closed Transduction System	King Faisal Specialist Hospital and Research Centre	Completed	CD19-CART	1, 2	2191301	KFSH&RC-R
Phase I/II Study of a Lentigen® CD19 Chimeric Antigen Receptor (CAR) T Cells in Adult patients with relapsed/refractory CD19 Positive Acute Lymphoblastic Leukemia (ALL) using a Closed Transduction System	King Faisal Specialist Hospital and Research Centre	Completed	CD19-CART	1/2	2191207	KFSH&RC-R
Phase 3, Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of PF-07055480 (Recombinant AAV2/6 Human Factor VIII Gene Therapy) in Adult Male Participants with Moderately Severe to Severe Hemophilia A (FVIII:C≤1%)	Pfizer	Ongoing	PF-07055480 (formerly SB-525)	3	C3731003	King Faisal Specialist Hospital and Research Center (Riyadh)