The objective was To assess the efficacy and safety of initial combination therapy with sitagliptin(a Dipeptidyl Peptidase-4 Inhibitor) and metformin in patients with type 2 diabetes and inadequate glycemic control on diet and exercise.

September 15, 2007 - The U.S. Food and Drug Administration, the U.S equivalent to Saudi Food and Drug Authority (SFDA) has approved new indication of Evista (raloxifene hydrochloride) for reducing the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer. Evista is only the second drug approved to reduce the risk of breast cancer.

September 15, 2007, the US Food and drug Administration, the American's equivalent to the Saudi Food and Drug Authority (SFDA), announced important safety information regarding Fentanyl buccal tablet marketed under the trade name ( Fentora®) .

September 17, 2007, the US Food and drug Administration, the American's equivalent to the Saudi Food and Drug Authority (SFDA), announced important safety information regarding Haloperidol marketed under the trade name ( Haldol®).

Venous thromboembolism is treated with unfractionated heparin or low-molecular-weight heparin, followed by a vitamin K antagonist. Researchers investigated the potential use of idraparinux, a long-acting inhibitor of activated factor X, as a substitute for standard therapy.

Although amiodarone is approved by the US Food and Drug Administration only for refractory ventricular arrhythmias, it is one of the most frequently prescribed antiarrhythmic medications in the United States.

Objective was To evaluate and synthesize evidence regarding optimal use of amiodarone for various arrhythmias.

September 12, 2007 – The U.S Food and Drug Administration (FDA), the equivalent to the Saudi Food and Drug Authority (SFDA) , has requested manufacturers of all gadolinium-based contrast agents (GBCAs) to add a new Boxed Warning and new Warnings about Nephrogenic Systemic Fibrosis (NSF) to the full prescribing information for all gadolinium-based contrast agents (GBCAs) (Magnevist, MultiHance, Omniscan, OptiMARK, ProHance) used in Magnetic Resonance Imaging (MRI).

October 1, 2007, the US Food and drug Administration, the American's equivalent to the Saudi Food and Drug Authority (SFDA), announced ongoing review of safety information of Bisphosphonates Class (Alendronate (Fosamax, Fosamax once weekly), Etidronate (Didronel), Ibandronate (Boniva), Pamidronate (Aredia), Risedronate (Actonel, Actonel W/Calcium), Tiludronate (Skelid), and Zoledronic acid (Aclasta, Zometa).

October, 18th , 2007, Health Canada, the Canadian equivalent of the Saudi Food and Drug Authority (SFDA), announced Important Safety Information on Definity (Perflutren Injectable Suspension).

Physical function and exercise capacity decline with age and are a major source of disability in older people. Recent evidence suggests a potential role for the renin – angiotensin system in modulating muscle function. researchers sought to examine the effect of the angiotensin-convertingenzyme (ACE) inhibitor perindopril on physical function in elderly people with functional impairment who had no heart failure or left ventricular systolic dysfunction.