Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Efficacy and Safety of Upadacitinib in Adult and Adolescent Subjects with Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy	Abbvie	Ongoing	Upadacitinib (Rinvoq)	3	M23-698	King Faisal Specialist Hospital and Research Center (Riyadh), King Faisal Specialist Hospital and Research Center (Jeddah), King Khalid University Hospital (Riyadh), King Abdulaziz Medical City NG (Jeddah)
A Phase 3, single-arm, multicenter, multinational, open label,one-way crossover study to investigate the efficacy and safety of fitusiran prophylaxis in male participants aged ≥ 12 years with severe hemophilia A or B, with or without inhibitory antibodies to factor VIII or IX	Sanofi	Ongoing	Fitusiran	3	EFC17574	King Faisal Specialist Hospital and Research Center (Riyadh) , King Abdulaziz University Hospital (Jeddah)
A single arm, multicentre observational study to evaluate effectiveness of pegcetacoplan under real world conditions in patients with paroxysmal nocturnal hemoglobinuria (PNH) COMPLETE	Sobi - Swedish Orphan Biovitrum AG	Ongoing	pegcetacoplan (ASPAVELI)	4	Sobi.PEGCE	King Faisal Specialist Hospital and Research Center (Jeddah),King Faisal Specialist Hospital and Research Center (Riyadh),King Faisal Specialist Hospital and Research Center (Madinah)
The Effect of Black Seeds (Nigella Sativa) on Prediabetic Overweight and Obese Adolescents	Imam Abdulrhman bin Faisal university	Ongoing	Nigella sativa seeds	3	2230500005	Family and Community Medicine Center (Dammam)
A Randomized, Double Blinded, Comparative Observational Interventional Study to Assess The Safety And Immunogenicity Of Hepatitis B Vaccine In Newborns / Adolescents And Adults Six Months Post Vaccination	Arab Company for Pharmaceutical products	Ongoing	EUVAX B VACCINE	4	HBV-001	King Fahad Medical City (Riyadh),General Medical Polyclinic (Jeddah) ,Dafa Special Polyclinic
Impact of using Zinc Oxide versus Moist Exposed Wound Ointment (MEBO) in treatment of second stage pressure ulcer: A randomized control clinical trial	King Abdullah Medical City (Makkah)	Ongoing	MEBO and Zinc oxide topical	3	Version 5	King Abdullah Medical City (Makkah)
A Proof of Concept, Phase IIa, Open Label Study to Evaluate the Safety and Efficacy of Subcutaneous Implants of Afamelanotide in Patients with Xeroderma Pigmentosum (XP)	CLINUVEL EUROPE LIMITED	Terminated	Afamelanotide	2a	CUV156	King Faisal Specialist Hospital and Research Center (Riyadh)
A randomized, double-blind, double-dummy, parallel-group study, comparing the efficacy and safety of remibrutinib versus teriflunomide in participants with relapsing multiple sclerosis, followed by extended treatment with open-label remibrutinib	Novartis	Ongoing	remibrutinib	3	CLOU064C123	King Faisal Specialist Hospital and Research Center (Jeddah) - King Abdulaziz Medical City NG (Jeddah) - King Abdulaziz Medical City NG (Riyadh)
An Open-label Extension Trial to Evaluate the Long-term Safety of KVD900, an Oral Plasma Kallikrein Inhibitor, for On-demand Treatment of Angioedema Attacks in Adolescent and Adult Patients with Hereditary Angioedema Type I or II	KalVista Pharmaceuticals Ltd	Ongoing	Sebetralstat	3	KVD900-302	King Faisal Specialist Hospital and Research Center (Riyadh)
A prospective observational international study of cabozantinib tablets in combination with nivolumab as first-line treatment of advanced renal cell carcinoma in adults	Ipsen Pharma	Ongoing	Cabozantinib	4	CLIN-60000	King Abdulaziz Medical City NG (Riyadh)