| A Phase III, Multicenter, Randomized, Parallel Group, Double Blind, Double Dummy, Active Controlled Study of Evobrutinib Compared with Teriflunomide, in Participants with Relapsing Multiple Sclerosis to Evaluate Efficacy and Safety. |
Ongoing |
Evobrutinib |
3 |
MS200527ˍ0082 |
King Faisal Specialist Hospital and Research Center (Jeddah) |
| "A phase III, Multicenter, Randomized, Double-blind Study to Assess Efficacy and Safety of Two Doses of Crizanlizumab versus placebo, with or without Hydroxyurea/Hydroxycarbamide Therapy, in Adolescent and Adult Sickle Cell Disease Patients with Vaso-Occlusive Crises (STAND)" |
Ongoing |
Crizanlizumab |
3 |
CSEG101A2301 |
King Fahad Medical City (Riyadh) |
| A PHASE III, MULTICENTER, RANDOMISED, DOUBLEBLIND, PLACEBOCONTROLLED STUDY OF ATEZOLIZUMAB (ANTI−PDL1 ANTIBODY) IN COMBINATION WITH PACLITAXEL COMPARED WITH PLACEBO WITH PACLITAXEL FOR PATIENTS WITH PREVIOUSLY UNTREATED INOPERABLE LOCALLY ADVANCED OR METASTATIC TRIPLE NEGATIVE BREAST CANCER |
Completed |
ATEZOLIZUMAB / PACLITAXEL |
3 |
MO39196 |
IMC (Closed), KFSH (Closed), KFMC (Closed) |
| A Phase III, Multicenter, Double-Blind, Randomized, Placebo-Controlled Clinical Trial to Evaluate the Safety and Efficacy of Sitagliptin in Pediatric Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control |
Ongoing |
Sitagliptin |
3 |
MK0431-083 |
NGHA-R |
| A Phase III, Multicenter, Double-Blind, Randomized, Placebo-Controlled Clinical Trial to Evaluate the Safety and Efficacy of MK-0431A (A Fixed-Dose Combination Tablet of Sitagliptin and Metformin) in Pediatric Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Therapy (Alone or in Combination With Insulin) |
Completed |
MK-0431A (Sitagliptin / Metformin) |
3 |
MK0431-170 |
NGHA-R |
| A Phase III, Double-Blind, Randomised Study to Assess the Efficacy and Safety of AZD9291 versus a Standard of Care Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor as First-Line Treatment in Patients with Epidermal Growth Factor Receptor Mutation Positive, Locally Advanced or Metastatic Non-Small Cell Lung Cancer |
Completed |
AZD9291 |
3 |
D5160C00007 |
KFSH&RC-R |
| A Phase III Study of Trastuzumab Deruxtecan (T-DXd) with or without Pertuzumab versus Taxane, Trastuzumab and Pertuzumab in HER2-positive, First-line Metastatic Breast Cancer (DESTINY-Breast09) |
Ongoing |
Trastuzumab-deruxtecan (Enhertu) |
3 |
D967UC00001 |
King Fahad Specialist Hospital (Dammam) |
| A Phase III Randomized, Open-Label, Multi-Center, Global Study of MEDI4736 in Combination With Tremelimumab Therapy Versus Standard of Care Platinum-Based Chemotherapy in First-Line Treatment of Patients With Advanced or Metastatic Non Small-Cell Lung Cancer (NSCLC) (NEPTUNE) |
Completed |
MEDI4736+Tremelimumab |
3 |
D419AC00003 |
KKUH |
| A phase III randomized open-label multi-center study of ruxolitinib vs. best available therapy in patients with corticosteroid-refractory acute graft vs. host disease after allogenic stem cell transplantation |
Completed |
Ruxolitinib (INC424) (Jakavi) |
3 |
CINC424C2301 |
KFSH&RC-R |
| A phase III randomized open-label multi-center study of ruxolitinib vs. best available therapy in patients with corticosteroid-refractory chronic graft versus host disease after allogenic stem cell transplantation |
Ongoing |
Ruxolitinib (INC424) (Jakavi) |
3 |
CINC424D2301 |
KFSH & RC-R |
