Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
Single arm Phase I/II study of the safety, tolerability and efficacy of the Tocilizumab followed by cisplatin/docetaxel in patients with triple negative locally advanced breast cancer	King Faisal Specialist Hospital and Research Centre	Ongoing	• TOCILIZUMAB (ACTEMRA)• DOCETAXEL (TAXOTERE)• CISPLATIN	2a	2181156	King Faisal Specialist Hospital and Research Center (Riyadh)
Re-challenge therapy with chemotherapy and panitumumab in metastatic colorectal cancer patients treated with an anti-EGFR therapy in 1st line treatment: a phase II multicentre study.	King Abdullah Medical City, Holy Capital	Ongoing	• PANITUMUMAB• OXALIPLATIN• irinotecan• FLOUROURACIL	2	19-504	King Abdullah Medical City (Makkah)
An Open-Label, Randomized, Multicenter, Active-Controlled, Parallel-Group Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 in Pediatric Subjects Aged 10 to Less Than 18 Years for the Treatment of Relapsing-Remitting Multiple Sclerosis, With Optional Open-Label Extension	Biogen	Ongoing	Interferon beta-1a	3	105MS306	King Faisal Specialist Hospital and Research Center (Jeddah), King Khalid University Hospital (Riyadh)
"A multicenter, multinational, prospective, interventional,single-arm, Phase IV study evaluating the clinicalefficacy and safety of 26 weeks of treatment with insulin glargine 300 U/mL (Gla-300) in patients with Type 2 diabetes mellitus uncontrolled on basal insulin"	SANOFI	Ongoing	TOUJEO	4	LPS15396	Sultan bin Abdulaziz Humanitarian city (Riyadh)
A prospective Randomized study of General Anesthesia versus Anesthetist Administered sedation for ERCP	King Abdullah Medical City (Makkah)	Ongoing	FENTANYL/ CISATRACURIUM/ SEVOFLURANE	4	18-492	King Abdullah Medical City (Makkah)
"A multi-centre prospective non-interventional studyinvestigating the clinical effectiveness of Ryzodeg® (InsulinDegludec/Insulin Aspart) in patients with type 2 diabetesmellitus in a real-world setting"	Novo Nordisk	Ongoing	Ryzodeg Flex Touch	4	NN54014525	King Abdulaziz University Hospital (Jeddah), Ghassan Najeeb Pharaon hospital (Jeddah), Saudi German Hospital (Jeddah), Umm Al-Qura University (Makkah), Dallah Hospital (Riyadh), Riyadh Care Hospital (Riyadh), Specialized Medical Center (Riyadh), King Abdulaziz Medical City NG (Riyadh)
CRAD001H2406- A long-term non-interventional observational study in Living Donor Liver Transplant Recipients (LDLTRs) with primary hepatocellular carcinoma (HCC) treated with Certican® / Zortress® (everolimus; EVR) plus reduced tacrolimus (rTAC) versus standard tacrolimus (sTAC) control	Novartis	Ongoing	• everolimus • reduced tacrolimus	4	CRAD001H24	King Faisal Specialist Hospital and Research Center (Riyadh)
A prospective, multicenter, observational study to evaluate patients’ quality oflife in routine clinical practice in patients with relapsing-remitting multiplesclerosis (RRMS) treated with LEMTRADA®	Sanofi	Ongoing	alemtuzumab	4	OBS15590	Al-Noor Specialist Hospital (Makkah), King Khalid University Hospital (Riyadh), King Saud Medical City (Riyadh), King Faisal Specialist Hospital and Research Center (Jeddah)
An Observational Registry of Abatacept in Patients with Juvenile Idiopathic Arthritis	Bristol-Myers Squibb	Ongoing	Abatacept	4	IM101240	King Abdulaziz Medical City NG (Riyadh)
An observational prospective study of switching asthma patients from a fixed-dose combination (FDC) Inhaled Corticosteroids [ICS] / Long-Acting Beta-Agonists [LABA] therapy delivered by pMDI Seretide® Evohaler to ICS/LABA delivered by pMDI Flutiform®	Mundipharma	Ongoing	Flutiform	4	FLT18-KSA	King Fahad Medical City (Riyadh), Prince Sultan Military Medical City (Riyadh)