Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of A4250 in Children with Progressive Familial Intrahepatic Cholestasis Types 1 and 2 (PEDFIC 2)	Albireo	Ongoing	A4250	3	A4250-008	King Faisal Specialist Hospital and Research Center (Riyadh)
"ALL SCTped 2012 FORUMAllogeneic Stem Cell Transplantation in Children and Adolescents with Acute Lymphoblastic Leukaemia"	KAIMRC	Completed	• BUSULFAN• FLUDARABINE PHOSPHATE• ETOPOSIDE	3	CT17/016/R	King Abdulaziz Medical City NG (Riyadh)
Single arm Phase I/II study of the safety, tolerability and efficacy of the Tocilizumab followed by cisplatin/docetaxel in patients with triple negative locally advanced breast cancer	King Faisal Specialist Hospital and Research Centre	Ongoing	• TOCILIZUMAB (ACTEMRA)• DOCETAXEL (TAXOTERE)• CISPLATIN	2a	2181156	King Faisal Specialist Hospital and Research Center (Riyadh)
Re-challenge therapy with chemotherapy and panitumumab in metastatic colorectal cancer patients treated with an anti-EGFR therapy in 1st line treatment: a phase II multicentre study.	King Abdullah Medical City, Holy Capital	Ongoing	• PANITUMUMAB• OXALIPLATIN• irinotecan• FLOUROURACIL	2	19-504	King Abdullah Medical City (Makkah)
An Open-Label, Randomized, Multicenter, Active-Controlled, Parallel-Group Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 in Pediatric Subjects Aged 10 to Less Than 18 Years for the Treatment of Relapsing-Remitting Multiple Sclerosis, With Optional Open-Label Extension	Biogen	Ongoing	Interferon beta-1a	3	105MS306	King Faisal Specialist Hospital and Research Center (Jeddah), King Khalid University Hospital (Riyadh)
"A multicenter, multinational, prospective, interventional,single-arm, Phase IV study evaluating the clinicalefficacy and safety of 26 weeks of treatment with insulin glargine 300 U/mL (Gla-300) in patients with Type 2 diabetes mellitus uncontrolled on basal insulin"	SANOFI	Ongoing	TOUJEO	4	LPS15396	Sultan bin Abdulaziz Humanitarian city (Riyadh)
A prospective Randomized study of General Anesthesia versus Anesthetist Administered sedation for ERCP	King Abdullah Medical City (Makkah)	Ongoing	FENTANYL/ CISATRACURIUM/ SEVOFLURANE	4	18-492	King Abdullah Medical City (Makkah)
"A multi-centre prospective non-interventional studyinvestigating the clinical effectiveness of Ryzodeg® (InsulinDegludec/Insulin Aspart) in patients with type 2 diabetesmellitus in a real-world setting"	Novo Nordisk	Ongoing	Ryzodeg Flex Touch	4	NN54014525	King Abdulaziz University Hospital (Jeddah), Ghassan Najeeb Pharaon hospital (Jeddah), Saudi German Hospital (Jeddah), Umm Al-Qura University (Makkah), Dallah Hospital (Riyadh), Riyadh Care Hospital (Riyadh), Specialized Medical Center (Riyadh), King Abdulaziz Medical City NG (Riyadh)
CRAD001H2406- A long-term non-interventional observational study in Living Donor Liver Transplant Recipients (LDLTRs) with primary hepatocellular carcinoma (HCC) treated with Certican® / Zortress® (everolimus; EVR) plus reduced tacrolimus (rTAC) versus standard tacrolimus (sTAC) control	Novartis	Ongoing	• everolimus • reduced tacrolimus	4	CRAD001H24	King Faisal Specialist Hospital and Research Center (Riyadh)
A prospective, multicenter, observational study to evaluate patients’ quality oflife in routine clinical practice in patients with relapsing-remitting multiplesclerosis (RRMS) treated with LEMTRADA®	Sanofi	Ongoing	alemtuzumab	4	OBS15590	Al-Noor Specialist Hospital (Makkah), King Khalid University Hospital (Riyadh), King Saud Medical City (Riyadh), King Faisal Specialist Hospital and Research Center (Jeddah)