Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
A three-arm, randomized, open-label, phase II study of everolimus in combination with exemestane versus everolimus alone versus capecitabine in the treatment of postmenupausal women with estrogen receptor postive, locally advanced, recurrent or metastatic breast cancer after recurrence or progression on prior letrozole or anastrozole.	Novartis	Rejected	Everolimus + Exemestane VS. Everolimus VS. Capecitabine	2	CRAD001Y2201	KFSH & RC-R
A single-arm, prospective, multicentre, open-label study to evaluate ofatumumab treatment effectiveness and patient reported outcomes in patients with relapsing multiple sclerosis transitioning from dimethyl fumarate or fingolimod therapy	Novartis	Ongoing	Ofatumumab	3b	COMB157G23101	King Faisal Specialist Hospital and Research Center (Jeddah)
A SINGLE-ARM, MULTICENTER PHASE IIIB CLINICAL TRIAL TO EVALUATE THE SAFETY AND TOLERABILITY OF PROPHYLACTIC EMICIZUMAB IN HEMOPHILIA A PATIENTS WITH INHIBITORS	Roche	Completed	Emicizumab	3	MO39129	KFSH & RC-R
A Randomized, Open-Label, Phase 3 Study of Abemaciclib combined with Standard Adjuvant Endocrine Therapy versus Standard Endocrine Therapy Alone in Patients with High Risk Node Positive Early Stage Hormone Receptor Positive, Human Epidermal Receptor 2 Negative Breast Cancer	Eli Lilly	Ongoing	abemaciclib	3	I3Y-MC-JPCF	KFMC
A Randomized, Open-label, Multicentral, Two Arm, Phase II Study to Investigate the Benefits of an Improved Deferasirox Formulation (Film-coated Tablet)	Novartis	Completed	Deferasirox dispersible tablet / Defearisox film-coated tablet	2	CICL670F2201	KKUH
A Randomized, Open-label Trial of Paritaprevir Plus Ritonavir Plus Ombitasvir in the Treatment of HCV Genotype 4 Infected Patients with Stage 4-5 Chronic Kidney Disease	Abbvie Biopharmaceuticals GmbH / KSU Liver Disease Research Center	Ongoing	ombitasvir \ paritaprevir \ ritonavir	3	Version 1.3.1	NGHA-J
A Randomized, Open-label Phase III Intergroup Study: Effect of Adding Bevacizumab to Cross Over Fluoropyrimidine Based Chemotherapy (CTx) in Patients With Metastatic Colorectal Cancer and Disease Progression Under First-line Standard CTx/Bevacizumab Combination	Roche	Completed	Bevacizumab	3	ML18147	KFSH
A Randomized, Multicenter, Open-Label, Phase 3 Study to Compare the Efficacy and Safety of Acalabrutinib (ACP-196) in Combination with Venetoclax with and without Obinutuzumab Compared to Investigator’s Choice of Chemoimmunotherapy in Subjects with Previously Untreated Chronic Lymphocytic Leukemia Without del(17p) or TP53 Mutation	Acerta Pharma BV (one of AstraZeneca AB group of companies)	Ongoing	Acalabrutinib	3	D8221C00001	KFSH
A RANDOMIZED, MULTICENTER, OPEN-LABEL CROSS-OVER STUDY TO EVALUATE PATIENT PREFERENCE AND SATISFACTION OF SUBCUTANEOUS ADMINISTRATION OF THE FIXED-DOSE COMBINATION OF PERTUZUMAB AND TRASTUZUMAB IN PATIENTS WITH HER2-POSITIVE EARLY BREAST CANCER	Roche	Completed	Trastuzumab & Pertuzumab	2	MO40628	KFSH & KFMC
"A Randomized, Multi-Center Study to Evaluate Cardiovascular Outcomes With ITCA 650 in Patients Treated With Standard of Care for Type 2 Diabetes "	Intarcia Therapeutics	Completed	ITCA 650	3	ITCA 650-CLP-107	NGHA-J